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Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression
Histone deacetylases (HDACs) modulate chromatin structure and transcription, but little is known about their function in mammalian development. HDAC1 was implicated previously in the repression of genes required for cell proliferation and differentiation. Here we show that targeted disruption of bot...
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| Main Authors: | , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2002
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC126040/ https://ncbi.nlm.nih.gov/pubmed/12032080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.11.2672 |
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