Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression

Histone deacetylases (HDACs) modulate chromatin structure and transcription, but little is known about their function in mammalian development. HDAC1 was implicated previously in the repression of genes required for cell proliferation and differentiation. Here we show that targeted disruption of bot...

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Détails bibliographiques
Auteurs principaux: Lagger, Gerda, O’Carroll, Dónal, Rembold, Martina, Khier, Harald, Tischler, Julia, Weitzer, Georg, Schuettengruber, Bernd, Hauser, Christoph, Brunmeir, Reinhard, Jenuwein, Thomas, Seiser, Christian
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2002
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC126040/
https://ncbi.nlm.nih.gov/pubmed/12032080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.11.2672
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