Načítá se...

Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor

Rett syndrome (RTT) is a severe neurological disorder that is caused by mutations in the MECP2 gene. Many missense mutations causing RTT are clustered in the DNA-binding domain of MeCP2, suggesting that association with chromatin is critical for its function. We identified a second mutational cluste...

Celý popis

Uloženo v:

Podrobná bibliografie
Hlavní autoři:	Lyst, Matthew J, Ekiert, Robert, Ebert, Daniel H, Merusi, Cara, Nowak, Jakub, Selfridge, Jim, Guy, Jacky, Kastan, Nathaniel R, Robinson, Nathaniel D, de Lima Alves, Flavia, Rappsilber, Juri, Greenberg, Michael E, Bird, Adrian
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	2013
Témata:	Article
On-line přístup:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3786392/ https://ncbi.nlm.nih.gov/pubmed/23770565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3434
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo otaguje tento záznam!

Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor

Podobné jednotky