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Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery
Eukaryotic transcriptional repressors function by recruiting large co-regulatory complexes that target histone deacetylase enzymes to gene promoters/enhancers. Transcriptional repression complexes, assembled by the co-repressor NCoR, and its homologue SMRT, play critical roles in many processes incl...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3232451/ https://ncbi.nlm.nih.gov/pubmed/21240272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1983 |
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