Talin Dependent Mechanosensitivity of Cell Focal Adhesions

Por Yan, Jie, Yao, Mingxi, Goult, Benjamin T., Sheetz, Michael P.
Publicado no Cell Mol Bioeng (2014)

Mechanical activation of vinculin binding to talin locks talin in an unfolded conformation

Por Yao, Mingxi, Goult, Benjamin T., Chen, Hu, Cong, Peiwen, Sheetz, Michael P., Yan, Jie
Publicado em 2014

A novel interaction between FRMD7 and CASK: evidence for a causal role in idiopathic infantile nystagmus

Por Watkins, Rachel J., Patil, Rajashree, Goult, Benjamin T., Thomas, Mervyn G., Gottlob, Irene, Shackleton, Sue
Publicado em 2013

Subcellular Localization of Talin Is Regulated by Inter-domain Interactions

Por Banno, Asoka, Goult, Benjamin T., Lee, HoSup, Bate, Neil, Critchley, David R., Ginsberg, Mark H.
Publicado em 2012

The domain structure of talin: Residues 1815–1973 form a five-helix bundle containing a cryptic vinculin-binding site

Por Goult, Benjamin T., Gingras, Alexandre R., Bate, Neil, Barsukov, Igor L., Critchley, David R., Roberts, Gordon C.K.
Publicado em 2010

FERM-dependent E3 ligase recognition is a conserved mechanism for targeted degradation of lipoprotein receptors

Por Calkin, Anna C., Goult, Benjamin T., Zhang, Li, Fairall, Louise, Hong, Cynthia, Schwabe, John W. R., Tontonoz, Peter
Publicado em 2011

The structure and selectivity of the SR protein SRSF2 RRM domain with RNA

Por Phelan, Marie M., Goult, Benjamin T., Clayton, Jonathan C., Hautbergue, Guillaume M., Wilson, Stuart A., Lian, Lu-Yun
Publicado em 2012

The Structure of the Talin/Integrin Complex at a Lipid Bilayer: An NMR and MD Simulation Study

Por Kalli, Antreas C., Wegener, Kate L., Goult, Benjamin T., Anthis, Nicholas J., Campbell, Iain D., Sansom, Mark S.P.
Publicado em 2010

Talin Contains A C-Terminal Calpain2 Cleavage Site Important In Focal Adhesion Dynamics

Por Bate, Neil, Gingras, Alexandre R., Bachir, Alexia, Horwitz, Rick, Ye, Feng, Patel, Bipin, Goult, Benjamin T., Critchley, David R.
Publicado em 2012

Structure calculation, refinement and validation using CcpNmr Analysis

Por Skinner, Simon P., Goult, Benjamin T., Fogh, Rasmus H., Boucher, Wayne, Stevens, Tim J., Laue, Ernest D., Vuister, Geerten W.
Publicado no Acta Crystallogr D Biol Crystallogr (2015)

A direct interaction between fascin and microtubules contributes to adhesion dynamics and cell migration

Por Villari, Giulia, Jayo, Asier, Zanet, Jennifer, Fitch, Briana, Serrels, Bryan, Frame, Margaret, Stramer, Brian M., Goult, Benjamin T., Parsons, Maddy
Publicado no J Cell Sci (2015)

The IDOL–UBE2D complex mediates sterol-dependent degradation of the LDL receptor

Por Zhang, Li, Fairall, Louise, Goult, Benjamin T., Calkin, Anna C., Hong, Cynthia, Millard, Christopher J., Tontonoz, Peter, Schwabe, John W.R.
Publicado em 2011

The Talin Head Domain Reinforces Integrin-Mediated Adhesion by Promoting Adhesion Complex Stability and Clustering

Por Ellis, Stephanie J., Lostchuck, Emily, Goult, Benjamin T., Bouaouina, Mohamed, Fairchild, Michael J., López-Ceballos, Pablo, Calderwood, David A., Tanentzapf, Guy
Publicado no PLoS Genet (2014)

The mechanical response of talin

Por Yao, Mingxi, Goult, Benjamin T., Klapholz, Benjamin, Hu, Xian, Toseland, Christopher P., Guo, Yingjian, Cong, Peiwen, Sheetz, Michael P., Yan, Jie
Publicado no Nat Commun (2016)

A Conserved Lipid-binding Loop in the Kindlin FERM F1 Domain Is Required for Kindlin-mediated αIIbβ3 Integrin Coactivation

Por Bouaouina, Mohamed, Goult, Benjamin T., Huet-Calderwood, Clotilde, Bate, Neil, Brahme, Nina N., Barsukov, Igor L., Critchley, David R., Calderwood, David A.
Publicado em 2012

Mzt1/Tam4, a fission yeast MOZART1 homologue, is an essential component of the γ-tubulin complex and directly interacts with GCP3(Alp6)

Por Dhani, Deepsharan K., Goult, Benjamin T., George, Gifty M., Rogerson, Daniel T., Bitton, Danny A., Miller, Crispin J., Schwabe, John W. R., Tanaka, Kayoko
Publicado em 2013

The Ansamycin Antibiotic, Rifamycin SV, Inhibits BCL6 Transcriptional Repression and Forms a Complex with the BCL6-BTB/POZ Domain

Por Evans, Sian E., Goult, Benjamin T., Fairall, Louise, Jamieson, Andrew G., Ko Ferrigno, Paul, Ford, Robert, Schwabe, John W. R., Wagner, Simon D.
Publicado em 2014

LD Motif Recognition by Talin: Structure of the Talin-DLC1 Complex

Por Zacharchenko, Thomas, Qian, Xiaolan, Goult, Benjamin T., Jethwa, Devina, Almeida, Teresa B., Ballestrem, Christoph, Critchley, David R., Lowy, Douglas R., Barsukov, Igor L.
Publicado no Structure (2016)

The Structure of the Talin Head Reveals a Novel Extended Conformation of the FERM Domain

Por Elliott, Paul R., Goult, Benjamin T., Kopp, Petra M., Bate, Neil, Grossmann, J. Günter, Roberts, Gordon C.K., Critchley, David R., Barsukov, Igor L.
Publicado em 2010

Central Region of Talin Has a Unique Fold That Binds Vinculin and Actin

Por Gingras, Alexandre R., Bate, Neil, Goult, Benjamin T., Patel, Bipin, Kopp, Petra M., Emsley, Jonas, Barsukov, Igor L., Roberts, Gordon C. K., Critchley, David R.
Publicado em 2010