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The domain structure of talin: Residues 1815–1973 form a five-helix bundle containing a cryptic vinculin-binding site
Talin is a large flexible rod-shaped protein that activates the integrin family of cell adhesion molecules and couples them to cytoskeletal actin. Its rod region consists of a series of helical bundles. Here we show that residues 1815–1973 form a 5-helix bundle, with a topology unique to talin which...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier Science B.V
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2887493/ https://ncbi.nlm.nih.gov/pubmed/20399778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2010.04.028 |
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