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The domain structure of talin: Residues 1815–1973 form a five-helix bundle containing a cryptic vinculin-binding site

Talin is a large flexible rod-shaped protein that activates the integrin family of cell adhesion molecules and couples them to cytoskeletal actin. Its rod region consists of a series of helical bundles. Here we show that residues 1815–1973 form a 5-helix bundle, with a topology unique to talin which...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Goult, Benjamin T., Gingras, Alexandre R., Bate, Neil, Barsukov, Igor L., Critchley, David R., Roberts, Gordon C.K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier Science B.V 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887493/
https://ncbi.nlm.nih.gov/pubmed/20399778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2010.04.028
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