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Relief of talin autoinhibition triggers a force-independent association with vinculin
Talin, vinculin, and paxillin are core components of the dynamic link between integrins and actomyosin. Here, we study the mechanisms that mediate their activation and association using a mitochondrial-targeting assay, structure-based mutants, and advanced microscopy. As expected, full-length vincul...
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| Publicado no: | J Cell Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7039207/ https://ncbi.nlm.nih.gov/pubmed/31816055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201903134 |
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