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Low-intensity pulsed ultrasound promotes cell motility through vinculin-controlled Rac1 GTPase activity

Low-intensity pulsed ultrasound (LIPUS) is a therapy used clinically to promote healing. Using live-cell imaging we show that LIPUS stimulation, acting through integrin-mediated cell-matrix adhesions, rapidly induces Rac1 activation associated with dramatic actin cytoskeleton rearrangements. Our stu...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Atherton, Paul, Lausecker, Franziska, Harrison, Andrew, Ballestrem, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536914/
https://ncbi.nlm.nih.gov/pubmed/28576970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.192781
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