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Phosphoinositides regulate force-independent interactions between talin, vinculin, and actin

Focal adhesions (FA) are large macromolecular assemblies which help transmit mechanical forces and regulatory signals between the extracellular matrix and an interacting cell. Two key proteins talin and vinculin connecting integrin to actomyosin networks in the cell. Both proteins bind to F-actin an...

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Publicat a:eLife
Autors principals: Kelley, Charlotte F, Litschel, Thomas, Schumacher, Stephanie, Dedden, Dirk, Schwille, Petra, Mizuno, Naoko
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7384861/
https://ncbi.nlm.nih.gov/pubmed/32657269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.56110
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