The Architecture of Talin1 Reveals an Autoinhibition Mechanism

Focal adhesions (FAs) are protein machineries essential for cell adhesion, migration, and differentiation. Talin is an integrin-activating and tension-sensing FA component directly connecting integrins in the plasma membrane with the actomyosin cytoskeleton. To understand how talin function is regul...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cell
Auteurs principaux: Dedden, Dirk, Schumacher, Stephanie, Kelley, Charlotte F., Zacharias, Martin, Biertümpfel, Christian, Fässler, Reinhard, Mizuno, Naoko
Format: Artigo
Langue:Inglês
Publié: Cell Press 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6856716/
https://ncbi.nlm.nih.gov/pubmed/31539492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.08.034
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