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Central Region of Talin Has a Unique Fold That Binds Vinculin and Actin
Talin is an adaptor protein that couples integrins to F-actin. Structural studies show that the N-terminal talin head contains an atypical FERM domain, whereas the N- and C-terminal parts of the talin rod include a series of α-helical bundles. However, determining the structure of the central part o...
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| Principais autores: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2937989/ https://ncbi.nlm.nih.gov/pubmed/20610383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.095455 |
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