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The Structure of the Talin/Integrin Complex at a Lipid Bilayer: An NMR and MD Simulation Study

Integrins are cell surface receptors crucial for cell migration and adhesion. They are activated by interactions of the talin head domain with the membrane surface and the integrin β cytoplasmic tail. Here, we use coarse-grained molecular dynamic simulations and nuclear magnetic resonance spectrosco...

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Detalhes bibliográficos
Main Authors: Kalli, Antreas C., Wegener, Kate L., Goult, Benjamin T., Anthis, Nicholas J., Campbell, Iain D., Sansom, Mark S.P.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032884/
https://ncbi.nlm.nih.gov/pubmed/20947017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2010.07.012
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