Insights into the Recruitment of Class IIa Histone Deacetylases (HDACs) to the SMRT/NCoR Transcriptional Repression Complex

Class IIa histone deacetylases repress transcription of target genes. However, their mechanism of action is poorly understood because they exhibit very low levels of deacetylase activity. The class IIa HDACs are associated with the SMRT/NCoR repression complexes and this may, at least in part, accou...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Hudson, Gregg M., Watson, Peter J., Fairall, Louise, Jamieson, Andrew G., Schwabe, John W. R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2015
Konular:
Gene Regulation
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505066/
https://ncbi.nlm.nih.gov/pubmed/26055705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.661058
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