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Insights into the Recruitment of Class IIa Histone Deacetylases (HDACs) to the SMRT/NCoR Transcriptional Repression Complex

Class IIa histone deacetylases repress transcription of target genes. However, their mechanism of action is poorly understood because they exhibit very low levels of deacetylase activity. The class IIa HDACs are associated with the SMRT/NCoR repression complexes and this may, at least in part, accou...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Hudson, Gregg M., Watson, Peter J., Fairall, Louise, Jamieson, Andrew G., Schwabe, John W. R.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505066/
https://ncbi.nlm.nih.gov/pubmed/26055705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.661058
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