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Insights into the Recruitment of Class IIa Histone Deacetylases (HDACs) to the SMRT/NCoR Transcriptional Repression Complex

Class IIa histone deacetylases repress transcription of target genes. However, their mechanism of action is poorly understood because they exhibit very low levels of deacetylase activity. The class IIa HDACs are associated with the SMRT/NCoR repression complexes and this may, at least in part, accou...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Hudson, Gregg M., Watson, Peter J., Fairall, Louise, Jamieson, Andrew G., Schwabe, John W. R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505066/
https://ncbi.nlm.nih.gov/pubmed/26055705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.661058
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