Involvement of the SMRT/NCoR–HDAC3 complex in transcriptional repression by the CNOT2 subunit of the human Ccr4–Not complex

In eukaryotic cells, the Ccr4–Not complex can regulate mRNA metabolism at various levels. Previously, we showed that promoter targeting of the CNOT2 subunit resulted in strong repression of RNA polymerase II transcription, which was sensitive to the HDAC (histone deacetylase) inhibitor, trichostatin...

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Bibliographische Detailangaben
Hauptverfasser: Jayne, Sandrine, Zwartjes, Carin G. M., Van Schaik, Frederik M. A., Timmers, H. Th. Marc
Format: Artigo
Sprache:Inglês
Veröffentlicht: Portland Press Ltd. 2006
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1559471/
https://ncbi.nlm.nih.gov/pubmed/16712523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060406
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