Cdc1p Is an Endoplasmic Reticulum-Localized Putative Lipid Phosphatase That Affects Golgi Inheritance and Actin Polarization by Activating Ca(2+) Signaling

di Losev, Eugene, Papanikou, Effrosyni, Rossanese, Olivia W., Glick, Benjamin S.
Pubblicazione 2008

Golgi Structure Correlates with Transitional Endoplasmic Reticulum Organization in Pichia pastoris and Saccharomyces cerevisiae

di Rossanese, Olivia W., Soderholm, Jon, Bevis, Brooke J., Sears, Irina B., O'Connor, James, Williamson, Edward K., Glick, Benjamin S.
Pubblicazione 1999

A Role for Actin, Cdc1p, and Myo2p in the Inheritance of Late Golgi Elements in Saccharomyces cerevisiae

di Rossanese, Olivia W., Reinke, Catherine A., Bevis, Brooke J., Hammond, Adam T., Sears, Irina B., O'Connor, James, Glick, Benjamin S.
Pubblicazione 2001

Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-mediated Activation

di Sun, Qi, Burke, Jason P., Phan, Jason, Burns, Michael C., Olejniczak, Edward T., Waterson, Alex G., Lee, Taekyu, Rossanese, Olivia W., Fesik, Stephen W.
Pubblicazione 2012

A high-throughput fluorescence polarization anisotropy assay for the 70N domain of Replication Protein A

di Souza-Fagundes, Elaine M., Frank, Andreas O., Feldkamp, Michael D., Dorset, Daniel C., Chazin, Walter J., Rossanese, Olivia W., Olejniczak, Edward T., Fesik, Stephen W.
Pubblicazione 2011

A Yeast t-SNARE Involved in Endocytosis

di Séron, Karin, Tieaho, Ville, Prescianotto-Baschong, Cristina, Aust, Thomas, Blondel, Marie-Odile, Guillaud, Philippe, Devilliers, Ginette, Rossanese, Olivia W., Glick, Benjamin S., Riezman, Howard, Keränen, Sirkka, Haguenauer-Tsapis, Rosine
Pubblicazione 1998

Discovery of Protein–Protein Interaction Inhibitors of Replication Protein A

di Patrone, James D., Kennedy, J. Phillip, Frank, Andreas O., Feldkamp, Michael D., Vangamudi, Bhavatarini, Pelz, Nicholas F., Rossanese, Olivia W., Waterson, Alex G., Chazin, Walter J., Fesik, Stephen W.
Pubblicazione 2013

Golgi enlargement in Arf-depleted yeast cells is due to altered dynamics of cisternal maturation

di Bhave, Madhura, Papanikou, Effrosyni, Iyer, Prasanna, Pandya, Koushal, Jain, Bhawik Kumar, Ganguly, Abira, Sharma, Chandrakala, Pawar, Ketakee, Austin, Jotham, Day, Kasey J., Rossanese, Olivia W., Glick, Benjamin S., Bhattacharyya, Dibyendu
Pubblicazione 2014

Approach for targeting Ras with small molecules that activate SOS-mediated nucleotide exchange

di Burns, Michael C., Sun, Qi, Daniels, R. Nathan, Camper, DeMarco, Kennedy, J. Phillip, Phan, Jason, Olejniczak, Edward T., Lee, Taekyu, Waterson, Alex G., Rossanese, Olivia W., Fesik, Stephen W.
Pubblicazione 2014

Discovery of a Potent Stapled Helix Peptide That Binds to the 70N Domain of Replication Protein A

di Frank, Andreas O., Vangamudi, Bhavatarini, Feldkamp, Michael D., Souza-Fagundes, Elaine M., Luzwick, Jessica W., Cortez, David, Olejniczak, Edward T., Waterson, Alex G., Rossanese, Olivia W., Chazin, Walter J., Fesik, Stephen W.
Pubblicazione 2014

High-throughput screening identifies small molecules that bind to the RAS:SOS:RAS complex and perturb RAS signaling

di Burns, Michael C., Howes, Jennifer E., Sun, Qi, Little, Andrew J., Camper, DeMarco V., Abbott, Jason R., Phan, Jason, Lee, Taekyu, Waterson, Alex G., Rossanese, Olivia W., Fesik, Stephen W.
Pubblicato in Anal Biochem (2018)

Discovery of a Potent Inhibitor of Replication Protein A Protein-Protein Interactions Using a Fragment Linking Approach

di Frank, Andreas O., Feldkamp, Michael D., Kennedy, J. Phillip, Waterson, Alex G., Pelz, Nicholas F., Patrone, James D., Vangamudi, Bhavatarini, Camper, DeMarco V., Rossanese, Olivia W., Chazin, Walter J., Fesik, Stephen W.
Pubblicazione 2013

Diphenylpyrazoles as Replication Protein A Inhibitors

di Waterson, Alex G., Kennedy, J. Phillip, Patrone, James D., Pelz, Nicholas F., Feldkamp, Michael D., Frank, Andreas O., Vangamudi, Bhavatarini, Souza-Fagundes, Elaine M., Rossanese, Olivia W., Chazin, Walter J., Fesik, Stephen W.
Pubblicato in ACS Med Chem Lett (2014)

Discovery of Quinazolines That Activate SOS1-Mediated Nucleotide Exchange on RAS

di Abbott, Jason R., Patel, Pratiq A., Howes, Jennifer E., Akan, Denis T., Kennedy, J. Phillip, Burns, Michael C., Browning, Carrie F., Sun, Qi, Rossanese, Olivia W., Phan, Jason, Waterson, Alex G., Fesik, Stephen W.
Pubblicato in ACS Med Chem Lett (2018)

Discovery of Tricyclic Indoles That Potently Inhibit Mcl-1 Using Fragment-Based Methods and Structure-Based Design

di Burke, Jason P., Bian, Zhiguo, Shaw, Subrata, Zhao, Bin, Goodwin, Craig M., Belmar, Johannes, Browning, Carrie F., Vigil, Dominico, Friberg, Anders, Camper, DeMarco V., Rossanese, Olivia W., Lee, Taekyu, Olejniczak, Edward T., Fesik, Stephen W.
Pubblicato in J Med Chem (2015)

DNA replication stress mediates APOBEC3 family mutagenesis in breast cancer

di Kanu, Nnennaya, Cerone, Maria Antonietta, Goh, Gerald, Zalmas, Lykourgos-Panagiotis, Bartkova, Jirina, Dietzen, Michelle, McGranahan, Nicholas, Rogers, Rebecca, Law, Emily K., Gromova, Irina, Kschischo, Maik, Walton, Michael I., Rossanese, Olivia W., Bartek, Jiri, Harris, Reuben S., Venkatesan, Subramanian, Swanton, Charles
Pubblicato in Genome Biol (2016)

Discovery of 2-Indole-acylsulfonamide Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods

di Pelz, Nicholas F., Bian, Zhiguo, Zhao, Bin, Shaw, Subrata, Tarr, James C., Belmar, Johannes, Gregg, Claire, Camper, DeMarco V., Goodwin, Craig M., Arnold, Allison L., Sensintaffar, John L., Friberg, Anders, Rossanese, Olivia W., Lee, Taekyu, Olejniczak, Edward T., Fesik, Stephen W.
Pubblicato in J Med Chem (2016)

Identification and Optimization of Anthranilic Acid-Based Inhibitors of Replication Protein A

di Patrone, James D., Pelz, Nicholas F., Bates, Brittney S., Souza-Fagundes, Elaine M., Vangamudi, Bhavatarini, Camper, Demarco V., Kuznetsov, Alexey G., Browning, Carrie F., Feldkamp, Michael D., Frank, Andreas O., Gilston, Benjamin A., Olejniczak, Edward T., Rossanese, Olivia W., Waterson, Alex G., Chazin, Walter J., Fesik, Stephen W.
Pubblicato in ChemMedChem (2016)

Discovery of Potent 2-Aryl-6,7-Dihydro-5H-Pyrrolo[1,2-a]imidazoles as WDR5 WIN-site Inhibitors Using Fragment-Based Methods and Structure-Based Design

di Wang, Feng, Jeon, Kyu Ok, Salovich, James M., Macdonald, Jonathan D., Alvarado, Joseph, Gogliotti, Rocco D., Phan, Jason, Olejniczak, Edward T., Sun, Qi, Wang, Shidong, Camper, DeMarco, Yuh, Joannes P., Shaw, J. Grace, Sai, Jiqing, Rossanese, Olivia W., Tansey, William P., Stauffer, Shaun R., Fesik, Stephen W.
Pubblicato in J Med Chem (2018)

Discovery of Dabrafenib: A Selective Inhibitor of Raf Kinases with Antitumor Activity against B-Raf-Driven Tumors

di Rheault, Tara R., Stellwagen, John C., Adjabeng, George M., Hornberger, Keith R., Petrov, Kimberly G., Waterson, Alex G., Dickerson, Scott H., Mook, Robert A., Laquerre, Sylvie G., King, Alastair J., Rossanese, Olivia W., Arnone, Marc R., Smitheman, Kimberly N., Kane-Carson, Laurie S., Han, Chao, Moorthy, Ganesh S., Moss, Katherine G., Uehling, David E.
Pubblicazione 2013