A novel class of H(3) antagonists derived from the natural product guided synthesis of unnatural analogs of the marine bromopyrrole alkaloid dispyrin

od Kennedy, J. Phillip, Conn, P. Jeffrey, Lindsley, Craig W.
izdano v Bioorg Med Chem Lett (2009)

Heterobiaryl and heterobiaryl ether derived M(5) positive allosteric modulators

od Bridges, Thomas M., Kennedy, J. Phillip, Hopkins, Corey R., Conn, P. Jeffrey, Lindsley, Craig W.
Izdano 2010

Chemical Lead Optimization of a pan G(q) mAChR M(1), M(3), M(5) Positive Allosteric Modulator (PAM) Lead. Part II. Development of potent and highly selective M(1) PAM

od Bridges, Thomas M., Kennedy, J. Phillip, Noetzel, Meredith J., Breininger, Micah L., Gentry, Patrick R., Conn, P. Jeffrey, Lindsley, Craig W.
Izdano 2010

Surface reengineering of RPA70N enables co-crystallization with an inhibitor of the RPA interaction motif of ATRIP

od Feldkamp, Michael D., Frank, Andreas O., Kennedy, J. Phillip, Patrone, James D., Vangamudi, Bhavatarini, Waterson, Alex G., Fesik, Stephen W., Chazin, Walter J.
Izdano 2013

Chemical Lead Optimization of a pan G(q) mAChR M(1), M(3), M(5) Positive Allosteric Modulator (PAM) Lead. Part I. Development of the first highly selective M(5) PAM

od Bridges, Thomas M., Kennedy, J. Phillip, Cho, Hyekyung P., Breininger, Micah L., Gentry, Patrick R., Hopkins, Corey R., Conn, P. Jeffrey, Lindsley, Craig W.
Izdano 2009

Akt-Dependent and Isoform-Specific Regulation of Dopamine Transporter Cell Surface Expression

od Speed, Nicole K., Matthies, Heinrich J. G., Kennedy, J. Phillip, Vaughan, Roxanne A., Javitch, Jonathan A., Russo, Scott J., Lindsley, Craig W., Niswender, Kevin, Galli, Aurelio
Izdano 2010

Insulin Reveals Akt Signaling as a Novel Regulator of Norepinephrine Transporter Trafficking and Norepinephrine Homeostasis

od Robertson, Sabrina D., Matthies, Heinrich J. G., Owens, W. Anthony, Sathananthan, Vidiya, Christianson, Nicole S. Bibus, Kennedy, J. Phillip, Lindsley, Craig W., Daws, Lynette C., Galli, Aurelio
Izdano 2010

Synthesis and Structure–Activity Relationships of Allosteric Potentiators of the M(4) Muscarinic Acetylcholine Receptor

od Kennedy, J. Phillip, Bridges, Thomas M., Gentry, Patrick R., Brogan, John T., Kane, Alexander S., Jones, Carrie K., Brady, Ashley E., Shirey, Jana K., Conn, P. Jeffrey, Lindsley, Craig W.
Izdano 2009

Discovery of Protein–Protein Interaction Inhibitors of Replication Protein A

od Patrone, James D., Kennedy, J. Phillip, Frank, Andreas O., Feldkamp, Michael D., Vangamudi, Bhavatarini, Pelz, Nicholas F., Rossanese, Olivia W., Waterson, Alex G., Chazin, Walter J., Fesik, Stephen W.
Izdano 2013

Approach for targeting Ras with small molecules that activate SOS-mediated nucleotide exchange

od Burns, Michael C., Sun, Qi, Daniels, R. Nathan, Camper, DeMarco, Kennedy, J. Phillip, Phan, Jason, Olejniczak, Edward T., Lee, Taekyu, Waterson, Alex G., Rossanese, Olivia W., Fesik, Stephen W.
Izdano 2014

Loss of Phosphatase and tensin homologue deleted on chromosome 10 engages ErbB3 and IGF-IR signaling to promote antiestrogen resistance in breast cancer

od Miller, Todd W., Pérez-Torres, Marianela, Narasanna, Archana, Guix, Marta, Stål, Olle, Pérez-Tenorio, Gizeh, Gonzalez-Angulo, Ana M., Hennessy, Bryan T., Mills, Gordon B., Kennedy, J. Phillip, Lindsley, Craig W., Arteaga, Carlos L.
Izdano 2009

Discovery of a Potent Inhibitor of Replication Protein A Protein-Protein Interactions Using a Fragment Linking Approach

od Frank, Andreas O., Feldkamp, Michael D., Kennedy, J. Phillip, Waterson, Alex G., Pelz, Nicholas F., Patrone, James D., Vangamudi, Bhavatarini, Camper, DeMarco V., Rossanese, Olivia W., Chazin, Walter J., Fesik, Stephen W.
Izdano 2013

Diphenylpyrazoles as Replication Protein A Inhibitors

od Waterson, Alex G., Kennedy, J. Phillip, Patrone, James D., Pelz, Nicholas F., Feldkamp, Michael D., Frank, Andreas O., Vangamudi, Bhavatarini, Souza-Fagundes, Elaine M., Rossanese, Olivia W., Chazin, Walter J., Fesik, Stephen W.
izdano v ACS Med Chem Lett (2014)

Discovery of Quinazolines That Activate SOS1-Mediated Nucleotide Exchange on RAS

od Abbott, Jason R., Patel, Pratiq A., Howes, Jennifer E., Akan, Denis T., Kennedy, J. Phillip, Burns, Michael C., Browning, Carrie F., Sun, Qi, Rossanese, Olivia W., Phan, Jason, Waterson, Alex G., Fesik, Stephen W.
izdano v ACS Med Chem Lett (2018)

Synthesis and SAR of selective muscarinic acetylcholine receptor subtype 1 (M1 mAChR) anatgonists

od Lewis, L. Michelle, Sheffler, Douglas, Williams, Richard, Bridges, Thomas M., Kennedy, J. Phillip, Brogan, J.T., Mulder, Matthew J., Williams, Lyndsey, Nalywajko, Natalia T., Niswender, Colleen M., Weaver, Charles D., Conn, P. Jeffrey, Lindsley, Craig W.
Izdano 2008

Synthesis and SAR of analogues of the M1 allosteric agonist TBPB. Part I. Exploration of alternative benzyl and privileged structure moieties

od Bridges, Thomas M., Brady, Ashley E., Kennedy, J. Phillip, Daniels, R. Nathan, Miller, Nicole R., Kim, Kwango, Breininger, Micah L., Gentry, Patrick R., Brogan, John T., Jones, Carrie K., Conn, P. Jeffrey, Lindsley, Craig W.
Izdano 2008

Centrally Active Allosteric Potentiators of the M(4) Muscarinic Acetylcholine Receptor Reverse Amphetamine-Induced Hyperlocomotor Activity in Rats

od Brady, Ashley E., Jones, Carrie K., Bridges, Thomas M., Kennedy, J. Phillip, Thompson, Analisa D., Heiman, Justin U., Breininger, Micah L., Gentry, Patrick R., Yin, Huiyong, Jadhav, Satyawan B., Shirey, Jana K., Conn, P. Jeffrey, Lindsley, Craig W.
Izdano 2008

Inhibition of mTOR is required for optimal antitumor effect of HER2 inhibitors against HER2-overexpressing cancer cells

od Miller, Todd W., Forbes, James T., Shah, Chirayu, Wyatt, Shelby K., Manning, H. Charles, Olivares, Maria G., Sanchez, Violeta, Dugger, Teresa C., Granja, Nara de Matos, Narasanna, Archana, Cook, Rebecca S., Kennedy, J. Phillip, Lindsley, Craig W., Arteaga, Carlos L.
Izdano 2009

Discovery and Characterization of Novel Subtype-Selective Allosteric Agonists for the Investigation of M(1) Receptor Function in the Central Nervous System

od Lebois, Evan P, Bridges, Thomas M, Lewis, L. Michelle, Dawson, Eric S, Kane, Alexander S., Xiang, Zixiu, Jadhav, Satyawan B, Yin, Huiyong, Kennedy, J. Phillip, Meiler, Jens, Niswender, Colleen M., Jones, Carrie K, Conn, P Jeffrey, Weaver, C David, Lindsley, Craig W
Izdano 2009

Discovery and development of a potent and highly selective small molecule muscarinic acetylcholine receptor subtype I (mAChR 1 or M(1)) antagonist in vitro and in vivo probe

od Weaver, C. David, Sheffler, Douglas J., Lewis, L. Michelle, Bridges, Thomas M., Williams, Richard, Nalywajko, Natalia T., Kennedy, J. Phillip, Mulder, Matthew M., Jadhav, Satyawan, Aldrich, Leslie A., Jones, Carrie K., Marlo, Joy, Niswender, Colleen M., Mock, Matthew M., Zheng, Fang, Conn, P. Jeffrey, Lindsley, Craig W.
izdano v Curr Top Med Chem (2009)