Promise of mGluR2/3 activators in psychiatry

Por Conn, P Jeffrey, Jones, Carrie K
Publicado em 2009

Muscarinic and Nicotinic Acetylcholine Receptor Agonists and Allosteric Modulators for the Treatment of Schizophrenia

Por Jones, Carrie K, Byun, Nellie, Bubser, Michael
Publicado em 2012

Subtype-selective allosteric modulators of muscarinic receptors for the treatment of CNS disorders

Por Conn, P. Jeffrey, Jones, Carrie K., Lindsley, Craig W.
Publicado em 2009

Activation of metabotropic glutamate receptors as a novel approach for the treatment of schizophrenia

Por Conn, P. Jeffrey, Lindsley, Craig W., Jones, Carrie K.
Publicado em 2008

Emerging Approaches for Treatment of Schizophrenia: Modulation of Cholinergic Signaling

Por Foster, Daniel J., Jones, Carrie K., Conn, P. Jeffrey
Publicado em 2012

Emerging Approaches for Treatment of Schizophrenia: Modulation of Glutamatergic Signaling

Por Noetzel, Meredith J., Jones, Carrie K., Conn, P. Jeffrey
Publicado em 2012

Continued optimization of the M(5) NAM ML375: Discovery of VU6008667, an M(5) NAM with high CNS penetration and a desired short half-life in rat for addiction studies

Por McGowan, Kevin M., Nance, Kellie D., Cho, Hykeyung P., Bridges, Thomas M., Jones, Carrie K., Conn, P. Jeffrey, Jones, Carrie K., Lindsley, Craig W.
Publicado no Bioorg Med Chem Lett (2017)

Roles of the M1 Muscarinic Acetylcholine Receptor Subtype in the Regulation of Basal Ganglia Function and Implications for the Treatment of Parkinson's Disease

Por Xiang, Zixiu, Thompson, Analisa D., Jones, Carrie K., Lindsley, Craig W., Conn, P. Jeffrey
Publicado em 2012

Selective Inhibition of M(5) Muscarinic Acetylcholine Receptors Attenuates Cocaine Self-Administration in Rats

Por Gunter, Barak W., Gould, Robert W., Bubser, Michael, McGowan, Kevin M., Lindsley, Craig W., Jones, Carrie K.
Publicado no Addict Biol (2017)

[(18)F]fallypride dopamine D2 receptor studies using delayed microPET scans and a modified Logan plot

Por Tantawy, Mohammed N., Jones, Carrie K., Baldwin, Ronald M., Ansari, M. Sib, Conn, P. Jeffrey, Kessler, Robert M., Peterson, Todd E.
Publicado em 2009

Total RNA Sequencing of Rett Syndrome Autopsy Samples Identifies the M(4) Muscarinic Receptor as a Novel Therapeutic Target

Por Gogliotti, Rocco G., Fisher, Nicole M., Stansley, Branden J., Jones, Carrie K., Lindsley, Craig W., Conn, P. Jeffrey, Niswender, Colleen M.
Publicado no J Pharmacol Exp Ther (2018)

Discovery of Molecular Switches that Modulate Modes of mGlu(5) Pharmacology In Vitro and In Vivo Within a Series of Functionalized, Regioisomeric 2- and 5-(Phenylethynyl) Pyrimidin...

Por Sharma, Sameer, Kedrowski, Jeffrey, Rook, Jerri M., Smith, Randy L., Jones, Carrie K., Rodriguez, Alice L., Conn, P. Jeffrey, Lindsley, Craig W.
Publicado em 2009

THE ANTIPSYCHOTIC POTENTIAL OF MUSCARINIC ALLOSTERIC MODULATION

Por Bridges, Thomas M., LeBois, Evan P., Hopkins, Corey R., Wood, Michael R., Jones, Carrie K., Conn, P. Jeffrey, Lindsley, Craig W.
Publicado no Drug News Perspect (2010)

Ligand-based virtual screen for the discovery of novel M(5) inhibitor chemotypes

Por Geanes, Alexander R., Cho, Hykeyung P., Nance, Kellie D., McGowan, Kevin M., Conn, P. Jeffrey, Jones, Carrie K., Meiler, Jens, Lindsley, Craig W.
Publicado no Bioorg Med Chem Lett (2016)

The metabotropic glutamate receptor 8 agonist (S)-3,4-DCPG reverses motor deficits in prolonged but not acute models of Parkinson’s disease

Por Johnson, Kari A., Jones, Carrie K., Tantawy, Mohammed N., Bubser, Michael, Marvanova, Marketa, Ansari, M. Sib, Baldwin, Ronald M., Conn, P. Jeffrey, Niswender, Colleen M.
Publicado em 2012

Impact of Isoflurane Anesthesia on D2 Receptor Occupancy by [(18)F]fallypride Measured by MicroPET With a Modified Logan Plot

Por Tantawy, Mohammed N., Peterson, Todd E., Jones, Carrie K., Johnson, Kari, Rook, Jerri M., Conn, P. Jeffrey, Baldwin, Ronald M., Ansari, M. Sib, Kessler, Robert M.
Publicado em 2011

Discovery and Characterization of ML398, a Potent and Selective Antagonist of the D(4) Receptor with in Vivo Activity

Por Berry, Cynthia B., Bubser, Michael, Jones, Carrie K., Hayes, John P., Wepy, James A., Locuson, Charles W., Daniels, J. Scott, Lindsley, Craig W., Hopkins, Corey R.
Publicado em 2014

A Rodent Model of Traumatic Stress Induces Lasting Sleep and Quantitative Electroencephalographic Disturbances

Por Nedelcovych, Michael T., Gould, Robert W., Zhan, Xiaoyan, Bubser, Michael, Gong, Xuewen, Grannan, Michael, Thompson, Analisa T., Ivarsson, Magnus, Lindsley, Craig W., Conn, P. Jeffrey, Jones, Carrie K.
Publicado no ACS Chem Neurosci (2015)

Pharmacological stimulation of metabotropic glutamate receptor type 4 in a rat model of Parkinson's disease and l-DOPA-induced dyskinesia: Comparison between a positive allosteric...

Por Iderberg, Hanna, Maslava, Natallia, Thompson, Analisa D., Bubser, Michael, Niswender, Colleen M., Hopkins, Corey R., Lindsley, Craig W., Conn, P. Jeffrey, Jones, Carrie K., Cenci, M. Angela
Publicado no Neuropharmacology (2015)

3-Cyano-5-fluoro-N-arylbenzamides as negative allosteric modulators of mGlu(5): Identification of easily prepared tool compounds with CNS exposure in rats

Por Felts, Andrew S., Lindsley, Stacey R., Lamb, Jeffrey P., Rodriguez, Alice L., Menon, Usha N., Jadhav, Satyawan, Jones, Carrie K., Conn, P. Jeffrey, Lindsley, Craig W., Emmitte, Kyle A.
Publicado em 2010