Pharmacological Treatments for Autism Spectrum Disorder: Will Emerging Approaches Yield New Treatments?

Por Gogliotti, Rocco G, Conn, P Jeffrey
Publicado no Neuropsychopharmacology (2016)

mGlu(5) positive allosteric modulation normalizes synaptic plasticity defects and motor phenotypes in a mouse model of Rett syndrome

Por Gogliotti, Rocco G., Senter, Rebecca K., Rook, Jerri M., Ghoshal, Ayan, Zamorano, Rocio, Malosh, Chrysa, Stauffer, Shaun R., Bridges, Thomas M., Bartolome, Jose M., Daniels, J. Scott, Jones, Carrie K., Lindsley, Craig W., Conn, P. Jeffrey, Niswender, Colleen M.
Publicado no Hum Mol Genet (2016)

mGlu(7) potentiation rescues cognitive, social, and respiratory phenotypes in a mouse model of Rett syndrome

Por Gogliotti, Rocco G., Senter, Rebecca K., Fisher, Nicole M., Adams, Jeffrey, Zamorano, Rocio, Walker, Adam G., Blobaum, Anna L., Engers, Darren W., Hopkins, Corey R., Daniels, J. Scott, Jones, Carrie K., Lindsley, Craig W., Xiang, Zixiu, Conn, P. Jeffrey, Niswender, Colleen M.
Publicado no Sci Transl Med (2017)

Discovery of VU6005649, a CNS Penetrant mGlu(7/8) Receptor PAM Derived from a Series of Pyrazolo[1,5-a]pyrimidines

Por Abe, Masahito, Seto, Mabel, Gogliotti, Rocco G., Loch, Matthew T., Bollinger, Katrina A., Chang, Sichen, Engelberg, Eileen M., Luscombe, Vincent B., Harp, Joel M., Bubser, Michael, Engers, Darren W., Jones, Carrie K., Rodriguez, Alice L., Blobaum, Anna L., Conn, P. Jeffrey, Niswender, Colleen M., Lindsley, Craig W.
Publicado no ACS Med Chem Lett (2017)