The Role of mGlu Receptors in Hippocampal Plasticity Deficits in Neurological and Psychiatric Disorders: Implications for Allosteric Modulators as Novel Therapeutic Strategies

Por Senter, Rebecca K., Ghoshal, Ayan, Walker, Adam G., Xiang, Zixiu, Niswender, Colleen M., Conn, P. Jeffrey
Publicado no Curr Neuropharmacol (2016)

β-arrestin2 couples metabotropic glutamate receptor 5 to neuronal protein synthesis and is a potential target to treat fragile X

Por Stoppel, Laura J., Auerbach, Benjamin D., Senter, Rebecca K., Preza, Anthony R., Lefkowitz, Robert J., Bear, Mark F.
Publicado no Cell Rep (2017)

Co-Activation of Metabotropic Glutamate Receptor 3 and Beta-Adrenergic Receptors Modulates Cyclic-AMP and Long-Term Potentiation, and Disrupts Memory Reconsolidation

Por Walker, Adam G, Sheffler, Douglas J, Lewis, Andrew S, Dickerson, Jonathan W, Foster, Daniel J, Senter, Rebecca K, Moehle, Mark S, Lv, Xiaohui, Stansley, Branden J, Xiang, Zixiu, Rook, Jerri M, Emmitte, Kyle A, Lindsley, Craig W, Conn, P Jeffrey
Publicado no Neuropsychopharmacology (2017)

mGlu(5) positive allosteric modulation normalizes synaptic plasticity defects and motor phenotypes in a mouse model of Rett syndrome

Por Gogliotti, Rocco G., Senter, Rebecca K., Rook, Jerri M., Ghoshal, Ayan, Zamorano, Rocio, Malosh, Chrysa, Stauffer, Shaun R., Bridges, Thomas M., Bartolome, Jose M., Daniels, J. Scott, Jones, Carrie K., Lindsley, Craig W., Conn, P. Jeffrey, Niswender, Colleen M.
Publicado no Hum Mol Genet (2016)

mGlu(7) potentiation rescues cognitive, social, and respiratory phenotypes in a mouse model of Rett syndrome

Por Gogliotti, Rocco G., Senter, Rebecca K., Fisher, Nicole M., Adams, Jeffrey, Zamorano, Rocio, Walker, Adam G., Blobaum, Anna L., Engers, Darren W., Hopkins, Corey R., Daniels, J. Scott, Jones, Carrie K., Lindsley, Craig W., Xiang, Zixiu, Conn, P. Jeffrey, Niswender, Colleen M.
Publicado no Sci Transl Med (2017)