Delay of cutaneous wound closure by morphine via local blockade of peripheral tachykinin release

Por Rook, Jerri M., McCarson, Kenneth E.
Publicado em 2007

Temporal effects of topical morphine application on cutaneous wound healing

Por Rook, Jerri M., Hasan, Wohaib, McCarson, Kenneth E.
Publicado em 2008

Morphine-induced early delays in wound closure: involvement of sensory neuropeptides and modification of neurokinin receptor expression

Por Rook, Jerri M., Hasan, Wohaib, McCarson, Kenneth E.
Publicado em 2009

Allosteric Modulation of Metabotropic Glutamate Receptors

Por Sheffler, Douglas J., Gregory, Karen J., Rook, Jerri M., Conn, P. Jeffrey
Publicado em 2011

Activation of M(1) and M(4) muscarinic receptors as potential treatments for Alzheimer’s disease and schizophrenia

Por Foster, Daniel J, Choi, Derrick L, Conn, P Jeffrey, Rook, Jerri M
Publicado em 2014

M(1) muscarinic activation induces long-lasting increase in intrinsic excitability of striatal projection neurons

Por Lv, Xiaohui, Dickerson, Jonathan W., Rook, Jerri M., Lindsley, Craig W., Conn, P. Jeffrey, Xiang, Zixiu
Publicado no Neuropharmacology (2017)

Discovery of Molecular Switches that Modulate Modes of mGlu(5) Pharmacology In Vitro and In Vivo Within a Series of Functionalized, Regioisomeric 2- and 5-(Phenylethynyl) Pyrimidin...

Por Sharma, Sameer, Kedrowski, Jeffrey, Rook, Jerri M., Smith, Randy L., Jones, Carrie K., Rodriguez, Alice L., Conn, P. Jeffrey, Lindsley, Craig W.
Publicado em 2009

Metabotropic glutamate receptor 3 activation is required for long-term depression in medial prefrontal cortex and fear extinction

Por Walker, Adam G., Wenthur, Cody J., Xiang, Zixiu, Rook, Jerri M., Emmitte, Kyle A., Niswender, Colleen M., Lindsley, Craig W., Conn, P. Jeffrey
Publicado no Proc Natl Acad Sci U S A (2015)

Role of mGlu(5) Receptors and Inhibitory Neurotransmission in M(1) Dependent Muscarinic LTD in the Prefrontal Cortex: Implications in Schizophrenia

Por Ghoshal, Ayan, Moran, Sean P., Dickerson, Jonathan W., Joffe, Max E., Grueter, Brad A., Xiang, Zixiu, Lindsley, Craig W., Rook, Jerri M., Conn, P. Jeffrey
Publicado no ACS Chem Neurosci (2017)

Impact of Isoflurane Anesthesia on D2 Receptor Occupancy by [(18)F]fallypride Measured by MicroPET With a Modified Logan Plot

Por Tantawy, Mohammed N., Peterson, Todd E., Jones, Carrie K., Johnson, Kari, Rook, Jerri M., Conn, P. Jeffrey, Baldwin, Ronald M., Ansari, M. Sib, Kessler, Robert M.
Publicado em 2011

An mGlu(5)-Positive Allosteric Modulator Rescues the Neuroplasticity Deficits in a Genetic Model of NMDA Receptor Hypofunction in Schizophrenia

Por Balu, Darrick T, Li, Yan, Takagi, Shunsuke, Presti, Kendall Taylor, Ramikie, Teniel S, Rook, Jerri M, Jones, Carrie K, Lindsley, Craig W, Conn, P Jeffrey, Bolshakov, Vadim Y, Coyle, Joseph T
Publicado no Neuropsychopharmacology (2016)

Development of Novel, CNS Penetrant Positive Allosteric Modulators for the Metabotropic Glutamate Receptor Subtype 1 (mGlu(1)), Based on an N-(3-Chloro-4-(1,3-dioxoisoindolin-2-yl)...

Por Garcia-Barrantes, Pedro M., Cho, Hyekyung P., Niswender, Colleen M., Byers, Frank W., Locuson, Charles W., Blobaum, Anna L., Xiang, Zixiu, Rook, Jerri M., Conn, P. Jeffrey, Lindsley, Craig W.
Publicado no J Med Chem (2015)

Relationship between In Vivo Receptor Occupancy and Efficacy of Metabotropic Glutamate Receptor Subtype 5 Allosteric Modulators with Different In Vitro Binding Profiles

Por Rook, Jerri M, Tantawy, Mohammed N, Ansari, Mohammad S, Felts, Andrew S, Stauffer, Shaun R, Emmitte, Kyle A, Kessler, Robert M, Niswender, Colleen M, Daniels, J Scott, Jones, Carrie K, Lindsley, Craig W, Conn, P Jeffrey
Publicado no Neuropsychopharmacology (2015)

Cholinergic projections to the substantia nigra reticulata inhibit dopamine modulation of basal ganglia through the M(4) muscarinic receptor

Por Moehle, Mark S., Pancani, Tristano, Byun, Nellie, Yohn, Samantha E., Wilson, George H., Dickerson, Johnathan W., Remke, Daniel H., Xiang, Zixiu, Niswender, Colleen M., Wess, Jurgen, Jones, Carrie K., Lindsley, Craig W., Rook, Jerri M., Conn, P. Jeffrey
Publicado no Neuron (2017)

Co-Activation of Metabotropic Glutamate Receptor 3 and Beta-Adrenergic Receptors Modulates Cyclic-AMP and Long-Term Potentiation, and Disrupts Memory Reconsolidation

Por Walker, Adam G, Sheffler, Douglas J, Lewis, Andrew S, Dickerson, Jonathan W, Foster, Daniel J, Senter, Rebecca K, Moehle, Mark S, Lv, Xiaohui, Stansley, Branden J, Xiang, Zixiu, Rook, Jerri M, Emmitte, Kyle A, Lindsley, Craig W, Conn, P Jeffrey
Publicado no Neuropsychopharmacology (2017)

Antipsychotic-like effects of M(4) positive allosteric modulators are mediated by CB(2) cannabinoid receptor-dependent inhibition of dopamine release

Por Foster, Daniel J., Wilson, Jermaine M., Remke, Daniel H., Muhammad, M. Suhaib, Uddin, M. Jashim, Wess, Jürgen, Patel, Sachin, Marnett, Lawrence J., Niswender, Colleen M., Jones, Carrie K., Xiang, Zixiu, Lindsley, Craig W., Rook, Jerri M., Conn, P. Jeffrey
Publicado no Neuron (2016)

mGlu(5) positive allosteric modulation normalizes synaptic plasticity defects and motor phenotypes in a mouse model of Rett syndrome

Por Gogliotti, Rocco G., Senter, Rebecca K., Rook, Jerri M., Ghoshal, Ayan, Zamorano, Rocio, Malosh, Chrysa, Stauffer, Shaun R., Bridges, Thomas M., Bartolome, Jose M., Daniels, J. Scott, Jones, Carrie K., Lindsley, Craig W., Conn, P. Jeffrey, Niswender, Colleen M.
Publicado no Hum Mol Genet (2016)

M(1)-positive allosteric modulators lacking agonist activity provide the optimal profile for enhancing cognition

Por Moran, Sean P., Dickerson, Jonathan W., Cho, Hyekyung P., Xiang, Zixiu, Maksymetz, James, Remke, Daniel H., Lv, Xiaohui, Doyle, Catherine A., Rajan, Deepa H., Niswender, Colleen M., Engers, Darren W., Lindsley, Craig W., Rook, Jerri M., Conn, P. Jeffrey
Publicado no Neuropsychopharmacology (2018)

Investigating Metabotropic Glutamate Receptor 5 Allosteric Modulator Cooperativity, Affinity, and Agonism: Enriching Structure-Function Studies and Structure-Activity Relationships

Por Gregory, Karen J., Noetzel, Meredith J., Rook, Jerri M., Vinson, Paige N., Stauffer, Shaun R., Rodriguez, Alice L., Emmitte, Kyle A., Zhou, Ya, Chun, Aspen C., Felts, Andrew S., Chauder, Brian A., Lindsley, Craig W., Niswender, Colleen M., Conn, P. Jeffrey
Publicado em 2012

Biotransformation of a Novel Positive Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Contributes to Seizure-Like Adverse Events in Rats Involving a Receptor Agon...

Por Bridges, Thomas M., Rook, Jerri M., Noetzel, Meredith J., Morrison, Ryan D., Zhou, Ya, Gogliotti, Rocco D., Vinson, Paige N., Xiang, Zixiu, Jones, Carrie K., Niswender, Colleen M., Lindsley, Craig W., Stauffer, Shaun R., Conn, P. Jeffrey, Daniels, J. Scott
Publicado em 2013