Therapeutic potential of targeting metabotropic glutamate receptors for Parkinson’s disease

Bằng Dickerson, Jonathan W, Conn, P Jeffrey
Được phát hành 2012

M(1) muscarinic activation induces long-lasting increase in intrinsic excitability of striatal projection neurons

Bằng Lv, Xiaohui, Dickerson, Jonathan W., Rook, Jerri M., Lindsley, Craig W., Conn, P. Jeffrey, Xiang, Zixiu
Xuất bản năm Neuropharmacology (2017)

(±)3,4-Methylenedioxymethamphetamine (“Ecstasy”) Treatment Modulates Expression of Neurotrophins and Their Receptors in Multiple Regions of Adult Rat Brain

Bằng Hemmerle, Ann M., Dickerson, Jonathan W., Herring, Nicole R., Schaefer, Tori L., Vorhees, Charles V., Williams, Michael T., Seroogy, Kim B.
Được phát hành 2012

CD8 T Cell-Initiated Vascular Endothelial Growth Factor Expression Promotes Central Nervous System Vascular Permeability under Neuroinflammatory Conditions

Bằng Suidan, Georgette L., Dickerson, Jonathan W., Chen, Yi, McDole, Jeremiah R., Tripathi, Pulak, Pirko, Istvan, Seroogy, Kim B., Johnson, Aaron J.
Được phát hành 2009

NEUROTOXIC (+)-METHAMPHETAMINE TREATMENT INCREASES BRAIN-DERIVED NEUROTROPHIC FACTOR AND TROPOMYOSIN RECEPTOR KINASE B (TrkB) EXPRESSION IN MULTIPLE BRAIN REGIONS

Bằng Braun, Amanda A., Herring, Nicole R., Schaefer, Tori L., Hemmerle, Ann M., Dickerson, Jonathan W., Seroogy, Kim B., Vorhees, Charles V., Williams, Michael T.
Được phát hành 2011

Preserved vascular integrity and enhanced survival following neuropilin-1 inhibition in a mouse model of CD8 T cell-initiated CNS vascular permeability

Bằng Suidan, Georgette L, Dickerson, Jonathan W, Johnson, Holly L, Chan, Theresa W, Pavelko, Kevin D, Pirko, Istvan, Seroogy, Kim B, Johnson, Aaron J
Được phát hành 2012

Role of mGlu(5) Receptors and Inhibitory Neurotransmission in M(1) Dependent Muscarinic LTD in the Prefrontal Cortex: Implications in Schizophrenia

Bằng Ghoshal, Ayan, Moran, Sean P., Dickerson, Jonathan W., Joffe, Max E., Grueter, Brad A., Xiang, Zixiu, Lindsley, Craig W., Rook, Jerri M., Conn, P. Jeffrey
Xuất bản năm ACS Chem Neurosci (2017)

Co-Activation of Metabotropic Glutamate Receptor 3 and Beta-Adrenergic Receptors Modulates Cyclic-AMP and Long-Term Potentiation, and Disrupts Memory Reconsolidation

Bằng Walker, Adam G, Sheffler, Douglas J, Lewis, Andrew S, Dickerson, Jonathan W, Foster, Daniel J, Senter, Rebecca K, Moehle, Mark S, Lv, Xiaohui, Stansley, Branden J, Xiang, Zixiu, Rook, Jerri M, Emmitte, Kyle A, Lindsley, Craig W, Conn, P Jeffrey
Xuất bản năm Neuropsychopharmacology (2017)

VU6007477, a Novel M(1) PAM Based on a Pyrrolo[2,3-b]pyridine Carboxamide Core Devoid of Cholinergic Adverse Events

Bằng Engers, Julie L., Childress, Elizabeth S., Long, Madeline F., Capstick, Rory A., Luscombe, Vincent B., Cho, Hekyung P., Dickerson, Jonathan W., Rook, Jerri M., Blobaum, Anna L., Niswender, Colleen M., Engers, Darren W., Conn, P. Jeffrey, Lindsley, Craig W.
Xuất bản năm ACS Med Chem Lett (2018)

M(1)-positive allosteric modulators lacking agonist activity provide the optimal profile for enhancing cognition

Bằng Moran, Sean P., Dickerson, Jonathan W., Cho, Hyekyung P., Xiang, Zixiu, Maksymetz, James, Remke, Daniel H., Lv, Xiaohui, Doyle, Catherine A., Rajan, Deepa H., Niswender, Colleen M., Engers, Darren W., Lindsley, Craig W., Rook, Jerri M., Conn, P. Jeffrey
Xuất bản năm Neuropsychopharmacology (2018)

Discovery of Tricyclic Triazolo- and Imidazopyridine Lactams as M(1) Positive Allosteric Modulators

Bằng Engers, Julie L., Bender, Aaron M., Kalbfleisch, Jacob J., Cho, Hyekyung P., Lingenfelter, Kaelyn S., Luscombe, Vincent B., Han, Changho, Melancon, Bruce J., Blobaum, Anna L., Dickerson, Jonathan W., Rook, Jerri M., Niswender, Colleen M., Emmitte, Kyle A., Conn, P. Jeffrey, Lindsley, Craig W.
Xuất bản năm ACS Chem Neurosci (2018)

The Metabotropic Glutamate Receptor 4-Positive Allosteric Modulator VU0364770 Produces Efficacy Alone and in Combination with l-DOPA or an Adenosine 2A Antagonist in Preclinical Ro...

Bằng Jones, Carrie K., Bubser, Michael, Thompson, Analisa D., Dickerson, Jonathan W., Turle-Lorenzo, Nathalie, Amalric, Marianne, Blobaum, Anna L., Bridges, Thomas M., Morrison, Ryan D., Jadhav, Satyawan, Engers, Darren W., Italiano, Kimberly, Bode, Jacob, Daniels, J. Scott, Lindsley, Craig W., Hopkins, Corey R., Conn, P. Jeffrey, Niswender, Colleen M.
Được phát hành 2012

A Novel M(1) PAM VU0486846 Exerts Efficacy in Cognition Models without Displaying Agonist Activity or Cholinergic Toxicity

Bằng Rook, Jerri M., Bertron, Jeanette L., Cho, Hyekyung P., Garcia-Barrantes, Pedro M., Moran, Sean P., Maksymetz, James T., Nance, Kellie D., Dickerson, Jonathan W., Remke, Daniel H., Chang, Sichen, Harp, Joel M., Blobaum, Anna L., Niswender, Colleen M., Jones, Carrie K., Stauffer, Shaun R., Conn, P. Jeffrey, Lindsley, Craig W.
Xuất bản năm ACS Chem Neurosci (2018)

Diverse Effects on M(1) Signaling and Adverse Effect Liability within a Series of M(1) Ago-PAMs

Bằng Rook, Jerri M., Abe, Masahito, Cho, Hyekyung P., Nance, Kellie D., Luscombe, Vincent B., Adams, Jeffrey J., Dickerson, Jonathan W., Remke, Daniel H., Garcia-Barrantes, Pedro M., Engers, Darren W., Engers, Julie L., Chang, Sichen, Foster, Jarrett J., Blobaum, Anna L., Niswender, Colleen M., Jones, Carrie K., Conn, P. Jeffrey, Lindsley, Craig W.
Xuất bản năm ACS Chem Neurosci (2017)

Biased mGlu(5) positive allosteric modulators provide in vivo efficacy without potentiating mGlu(5) modulation of NMDAR currents

Bằng Rook, Jerri M., Xiang, Zixiu, Lv, Xiaohui, Ghoshal, Ayan, Dickerson, Jonathan W., Bridges, Thomas M., Johnson, Kari A., Foster, Daniel J., Gregory, Karen J., Vinson, Paige N., Thompson, Analisa D., Byun, Nellie, Collier, Rebekah L., Bubser, Michael, Nedelcovych, Michael T., Gould, Robert W., Stauffer, Shaun R., Daniels, J. Scott, Niswender, Colleen M., Lavreysen, Hilde, Mackie, Claire, Conde-Ceide, Susana, Alcazar, Jesus, Bartolomé-Nebreda, José M., Macdonald, Gregor J., Steckler, Thomas, Jones, Carrie K., Lindsley, Craig W., Conn, P. Jeffrey
Xuất bản năm Neuron (2015)