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Preserved vascular integrity and enhanced survival following neuropilin-1 inhibition in a mouse model of CD8 T cell-initiated CNS vascular permeability
BACKGROUND: Altered permeability of the blood–brain barrier (BBB) is a feature of numerous neurological conditions including multiple sclerosis, cerebral malaria, viral hemorrhagic fevers and acute hemorrhagic leukoencephalitis. Our laboratory has developed a murine model of CD8 T cell-initiated cen...
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主要な著者: | , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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BioMed Central
2012
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3489603/ https://ncbi.nlm.nih.gov/pubmed/22985494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-218 |
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