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IB-10 A DUALITY OF ROLES FOR PERFORIN IN CD8+ T CELL- GLIOMA INTERACTIONS: CONTRIBUTIONS TO CYTOTOXICITY AND ALTERED VASCULAR PERMEABILITY
Glioblastoma multiforme (GBM) is a highly aggressive malignancy of the central nervous system that exhibits extensive vascularization and a high degree of invasiveness into the surrounding brain parenchyma. Recent evidence in both animal model systems and clinical trials have demonstrated the viabil...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4218215/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou257.10 |
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