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IB-10 A DUALITY OF ROLES FOR PERFORIN IN CD8+ T CELL- GLIOMA INTERACTIONS: CONTRIBUTIONS TO CYTOTOXICITY AND ALTERED VASCULAR PERMEABILITY

Glioblastoma multiforme (GBM) is a highly aggressive malignancy of the central nervous system that exhibits extensive vascularization and a high degree of invasiveness into the surrounding brain parenchyma. Recent evidence in both animal model systems and clinical trials have demonstrated the viabil...

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Detalhes bibliográficos
Main Authors: Renner, Danielle, Jin, Fang, Parney, Ian, Pirko, Istvan, Pavelko, Kevin, Johnson, Aaron
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218215/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou257.10
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