Group I and group II metabotropic glutamate receptor allosteric modulators as novel potential antipsychotics

Por Walker, Adam G., Conn, P. Jeffrey
Publicado no Curr Opin Pharmacol (2014)

Reduced expression of conditioned fear in the R6/2 mouse model of Huntington’s disease is related to abnormal activity in prelimbic cortex

Por Walker, Adam G., Ummel, Jason R., Rebec, George V.
Publicado em 2011

Targeting glutamate synapses in schizophrenia

Por Field, Julie R., Walker, Adam G., Conn, P. Jeffrey
Publicado em 2011

Dysregulated Neuronal Activity Patterns Implicate Corticostriatal Circuit Dysfunction in Multiple Rodent Models of Huntington's Disease

Por Miller, Benjamin R., Walker, Adam G., Barton, Scott J., Rebec, George V.
Publicado em 2011

Dysregulated Information Processing by Medium Spiny Neurons in Striatum of Freely Behaving Mouse Models of Huntington's Disease

Por Miller, Benjamin R., Walker, Adam G., Shah, Anand S., Barton, Scott J., Rebec, George V.
Publicado em 2008

Altered Information Processing in the Prefrontal Cortex of Huntington's Disease Mouse Models

Por Walker, Adam G., Miller, Benjamin R., Fritsch, Jenna N., Barton, Scott J., Rebec, George V.
Publicado em 2008

The Role of mGlu Receptors in Hippocampal Plasticity Deficits in Neurological and Psychiatric Disorders: Implications for Allosteric Modulators as Novel Therapeutic Strategies

Por Senter, Rebecca K., Ghoshal, Ayan, Walker, Adam G., Xiang, Zixiu, Niswender, Colleen M., Conn, P. Jeffrey
Publicado no Curr Neuropharmacol (2016)

Dysregulation of coordinated neuronal firing patterns in striatum of freely behaving transgenic rats that model Huntington’s disease

Por Miller, Benjamin R., Walker, Adam G., Fowler, Stephen C., von Hörsten, Stephan, Riess, Olaf, Johnson, Michael A., Rebec, George V.
Publicado em 2009

Chronic Stress Alters Neural Activity in Medial Prefrontal Cortex During Retrieval of Extinction

Por Wilber, Aaron A., Walker, Adam G., Southwood, Christopher J., Farrell, Mollee R., Lin, Grant L., Rebec, George V., Wellman, Cara L.
Publicado em 2010

Metabotropic glutamate receptor 3 activation is required for long-term depression in medial prefrontal cortex and fear extinction

Por Walker, Adam G., Wenthur, Cody J., Xiang, Zixiu, Rook, Jerri M., Emmitte, Kyle A., Niswender, Colleen M., Lindsley, Craig W., Conn, P. Jeffrey
Publicado no Proc Natl Acad Sci U S A (2015)

Activation of Metabotropic Glutamate Receptor 7 Is Required for Induction of Long-Term Potentiation at SC-CA1 Synapses in the Hippocampus

Por Klar, Rebecca, Walker, Adam G., Ghose, Dipanwita, Grueter, Brad A., Engers, Darren W., Hopkins, Corey R., Lindsley, Craig W., Xiang, Zixiu, Conn, P. Jeffrey, Niswender, Colleen M.
Publicado no J Neurosci (2015)

Co-Activation of Metabotropic Glutamate Receptor 3 and Beta-Adrenergic Receptors Modulates Cyclic-AMP and Long-Term Potentiation, and Disrupts Memory Reconsolidation

Por Walker, Adam G, Sheffler, Douglas J, Lewis, Andrew S, Dickerson, Jonathan W, Foster, Daniel J, Senter, Rebecca K, Moehle, Mark S, Lv, Xiaohui, Stansley, Branden J, Xiang, Zixiu, Rook, Jerri M, Emmitte, Kyle A, Lindsley, Craig W, Conn, P Jeffrey
Publicado no Neuropsychopharmacology (2017)

mGlu(7) potentiation rescues cognitive, social, and respiratory phenotypes in a mouse model of Rett syndrome

Por Gogliotti, Rocco G., Senter, Rebecca K., Fisher, Nicole M., Adams, Jeffrey, Zamorano, Rocio, Walker, Adam G., Blobaum, Anna L., Engers, Darren W., Hopkins, Corey R., Daniels, J. Scott, Jones, Carrie K., Lindsley, Craig W., Xiang, Zixiu, Conn, P. Jeffrey, Niswender, Colleen M.
Publicado no Sci Transl Med (2017)

Identification of Positive Allosteric Modulators VU0155094 (ML397) and VU0422288 (ML396) Reveals New Insights into the Biology of Metabotropic Glutamate Receptor 7

Por Jalan-Sakrikar, Nidhi, Field, Julie R., Klar, Rebecca, Mattmann, Margrith E., Gregory, Karen J., Zamorano, Rocio, Engers, Darren W., Bollinger, Sean R., Weaver, C. David, Days, Emily L., Lewis, L. Michelle, Utley, Thomas J., Hurtado, Miguel, Rigault, Delphine, Acher, Francine, Walker, Adam G., Melancon, Bruce J., Wood, Michael R., Lindsley, Craig W., Conn, P. Jeffrey, Xiang, Zixiu, Hopkins, Corey R., Niswender, Colleen M.
Publicado no ACS Chem Neurosci (2014)

Novel Allosteric Agonists of M(1) Muscarinic Acetylcholine Receptors Induce Brain Region-Specific Responses That Correspond with Behavioral Effects in Animal Models

Por Digby, Gregory J., Noetzel, Meredith J., Bubser, Michael, Utley, Thomas J., Walker, Adam G., Byun, Nellie E., Lebois, Evan P., Xiang, Zixiu, Sheffler, Douglas J., Cho, Hyekyung P., Davis, Albert A., Nemirovsky, Natali E., Mennenga, Sarah E., Camp, Bryan W., Bimonte-Nelson, Heather A., Bode, Jacob, Italiano, Kimberly, Morrison, Ryan, Daniels, J. Scott, Niswender, Colleen M., Olive, M. Foster, Lindsley, Craig W., Jones, Carrie K., Conn, P. Jeffrey
Publicado em 2012