Dysregulation of coordinated neuronal firing patterns in striatum of freely behaving transgenic rats that model Huntington’s disease

Altered neuronal activity in the striatum appears to be a key component of Huntington’s disease (HD), a fatal, neurodegenerative condition. To assess this hypothesis in freely behaving transgenic rats that model HD (tgHDs), we used chronically implanted micro-wires to record the spontaneous activity...

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Detalhes bibliográficos
Main Authors: Miller, Benjamin R., Walker, Adam G., Fowler, Stephen C., von Hörsten, Stephan, Riess, Olaf, Johnson, Michael A., Rebec, George V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787873/
https://ncbi.nlm.nih.gov/pubmed/19818852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2009.09.013
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