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Group I and group II metabotropic glutamate receptor allosteric modulators as novel potential antipsychotics
Recently, there has been a shift in the schizophrenia field focusing on restoring glutamate signaling. Extensive preclinical data suggests that mGlu(5) PAMs could have efficacy in all three symptom domains but there is concern of potential adverse effects. New insights into mechanisms underlying thi...
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| 發表在: | Curr Opin Pharmacol |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4318747/ https://ncbi.nlm.nih.gov/pubmed/25462291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2014.11.003 |
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