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Allosteric Modulation of Metabotropic Glutamate Receptors: Structural Insights and Therapeutic Potential

Allosteric modulation of G protein-coupled receptors (GPCRs) represents a novel approach to the development of probes and therapeutics that is expected to enable subtype-specific regulation of central nervous system target receptors. The metabotropic glutamate receptors (mGlus) are class C GPCRs tha...

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Hlavní autoři: Gregory, Karen J., Dong, Elizabeth N., Meiler, Jens, Conn, P. Jeffrey
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981682/
https://ncbi.nlm.nih.gov/pubmed/20637216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2010.07.007
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