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Allosteric Modulation of Metabotropic Glutamate Receptors: Structural Insights and Therapeutic Potential
Allosteric modulation of G protein-coupled receptors (GPCRs) represents a novel approach to the development of probes and therapeutics that is expected to enable subtype-specific regulation of central nervous system target receptors. The metabotropic glutamate receptors (mGlus) are class C GPCRs tha...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2981682/ https://ncbi.nlm.nih.gov/pubmed/20637216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2010.07.007 |
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