Evaluating phecodes, clinical classification software, and ICD-9-CM codes for phenome-wide association studies in the electronic health record

Por Wei, Wei-Qi, Bastarache, Lisa A., Carroll, Robert J., Marlo, Joy E., Osterman, Travis J., Gamazon, Eric R., Cox, Nancy J., Roden, Dan M., Denny, Joshua C.
Publicado no PLoS One (2017)

Discovery of the First Highly M5-Preferring Muscarinic Acetylcholine Receptor Ligand, an M5 Positive Allosteric Modulator Derived from a Series of 5-Trifluoromethoxy N-Benzyl Isati...

Por Bridges, Thomas M., Marlo, Joy E., Niswender, Colleen M., Jones, Carrie K., Jadhav, Satyawan B., Gentry, Patrick R., Plumley, Hyekyung C., Weaver, C. David, Conn, P. Jeffrey, Lindsley, Craig W.
Publicado em 2009

Discovery and development of a potent and highly selective small molecule muscarinic acetylcholine receptor subtype I (mAChR 1 or M(1)) antagonist in vitro and in vivo probe

Por Weaver, C. David, Sheffler, Douglas J., Lewis, L. Michelle, Bridges, Thomas M., Williams, Richard, Nalywajko, Natalia T., Kennedy, J. Phillip, Mulder, Matthew M., Jadhav, Satyawan, Aldrich, Leslie A., Jones, Carrie K., Marlo, Joy, Niswender, Colleen M., Mock, Matthew M., Zheng, Fang, Conn, P. Jeffrey, Lindsley, Craig W.
Publicado no Curr Top Med Chem (2009)

Discovery, characterization, and antiparkinsonian effect of novel positive allosteric modulators of metabotropic glutamate receptor 4

Por Niswender, Colleen M., Johnson, Kari A., Weaver, C. David, Jones, Carrie K., Xiang, Zixiu, Luo, Qingwei, Rodriguez, Alice L., Marlo, Joy E., de Paulis, Tomas, Thompson, Analisa D., Days, Emily L., Nalywajko, Tasha, Aust, Cheryl A., Williams, Michael Baxter, Ayala, Jennifer E., Williams, Richard, Lindsley, Craig W., Conn, P. Jeffrey
Publicado em 2008

Discovery and Characterization of Novel Allosteric Potentiators of M(1) Muscarinic Receptors Reveals Multiple Modes of Activity

Por Marlo, Joy E., Niswender, Colleen M., Days, Emily L., Bridges, Thomas M., Xiang, Yun, Rodriguez, Alice L., Shirey, Jana K., Brady, Ashley E., Nalywajko, Tasha, Luo, Qingwei, Austin, Cheryl A., Williams, Michael Baxter, Kim, Kwangho, Williams, Richard, Orton, Darren, Brown, H. Alex, Lindsley, Craig W., Weaver, C. David, Conn, P. Jeffrey
Publicado em 2009

Discovery of Novel Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5 Reveals Chemical and Functional Diversity and In Vivo Activity in...

Por Rodriguez, Alice L., Grier, Mark D., Jones, Carrie K., Herman, Elizabeth J., Kane, Alexander S., Smith, Randy L., Williams, Richard, Zhou, Ya, Marlo, Joy E., Days, Emily L., Blatt, Tasha N., Jadhav, Satyawan, Menon, Usha N., Vinson, Paige N., Rook, Jerri M., Stauffer, Shaun R., Niswender, Colleen M., Lindsley, Craig W., Weaver, C. David, Conn, P. Jeffrey
Publicado em 2010

Phenotype risk scores identify patients with unrecognized Mendelian disease patterns

Por Bastarache, Lisa, Hughey, Jacob J., Hebbring, Scott, Marlo, Joy, Zhao, Wanke, Ho, Wanting T., Van Driest, Sara L., McGregor, Tracy L., Mosley, Jonathan D., Wells, Quinn S., Temple, Michael, Ramirez, Andrea H., Carroll, Robert, Osterman, Travis, Edwards, Todd, Ruderfer, Douglas, Velez Edwards, Digna R., Hamid, Rizwan, Cogan, Joy, Glazer, Andrew, Wei, Wei-Qi, Feng, QiPing, Brilliant, Murray, Zhao, Zhizhuang J., Cox, Nancy J., Roden, Dan M., Denny, Joshua C.
Publicado no Science (2018)