Centrally Active Allosteric Potentiators of the M(4) Muscarinic Acetylcholine Receptor Reverse Amphetamine-Induced Hyperlocomotor Activity in Rats

Previous clinical and animal studies suggest that selective activators of M(1) and/or M(4) muscarinic acetylcholine receptors (mAChRs) have potential as novel therapeutic agents for treatment of schizophrenia and Alzheimer’s disease. However, highly selective centrally penetrant activators of either...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Brady, Ashley E., Jones, Carrie K., Bridges, Thomas M., Kennedy, J. Phillip, Thompson, Analisa D., Heiman, Justin U., Breininger, Micah L., Gentry, Patrick R., Yin, Huiyong, Jadhav, Satyawan B., Shirey, Jana K., Conn, P. Jeffrey, Lindsley, Craig W.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745822/
https://ncbi.nlm.nih.gov/pubmed/18772318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.140350
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires