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Allosteric activators of muscarinic receptors as novel approaches for treatment of CNS disordersw
Muscarinic acetylcholine receptors (mAChRs) represent exciting therapeutic targets for the treatment of multiple CNS disorders. The high degree of conservation of amino acids comprising the orthosteric acetylcholine (ACh) binding site between individual mAChR subtypes has hindered the development of...
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| Publicado no: | Mol Biosyst |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4780333/ https://ncbi.nlm.nih.gov/pubmed/20582339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c002938f |
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