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Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders
Despite G-protein-coupled receptors (GPCRs) being among the most fruitful targets for marketed drugs, intense discovery efforts for several GPCR subtypes have failed to deliver selective drug candidates. Historically, drug discovery programmes for GPCR ligands have been dominated by efforts to devel...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2907734/ https://ncbi.nlm.nih.gov/pubmed/19116626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd2760 |
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