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Development of allosteric modulators of GPCRs for treatment of CNS disorders
The discovery of allosteric modulators of G protein-coupled receptors (GPCRs) provides a promising new strategy with potential for developing novel treatments for a variety of central nervous system (CNS) disorders. Traditional drug discovery efforts targeting GPCRs have focused on developing ligand...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3875303/ https://ncbi.nlm.nih.gov/pubmed/24076101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2013.09.013 |
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