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Allosteric modulation of GPCRs: new insights and potential utility for treatment of schizophrenia and other CNS disorders
G-protein coupled receptors (GPCRs) play critical roles in regulating brain function. Recent advances have greatly expanded our understanding of these receptors as complex signaling machines that can adopt numerous conformations and modulate multiple downstream signaling pathways. While agonists and...
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| Publicado no: | Neuron |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5482176/ https://ncbi.nlm.nih.gov/pubmed/28472649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2017.03.016 |
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