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Allosteric Modulation of Class C GPCRs: A Novel Approach for the Treatment of CNS Disorders
Allosteric modulation has emerged as an innovative pharmacological approach to selectively activate or inhibit a number of Class C GPCRs. Of the Class C GPCRs, metabotropic glutamate (mGlu) receptors represent the most promising candidates for clinical success, and both positive allosteric modulator...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3779342/ https://ncbi.nlm.nih.gov/pubmed/24050278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ddtec.2012.10.007 |
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