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Allosteric modulation of GPCRs: new insights and potential utility for treatment of schizophrenia and other CNS disorders
G-protein coupled receptors (GPCRs) play critical roles in regulating brain function. Recent advances have greatly expanded our understanding of these receptors as complex signaling machines that can adopt numerous conformations and modulate multiple downstream signaling pathways. While agonists and...
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| Publicat a: | Neuron |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5482176/ https://ncbi.nlm.nih.gov/pubmed/28472649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2017.03.016 |
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