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Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders
Despite G-protein-coupled receptors (GPCRs) being among the most fruitful targets for marketed drugs, intense discovery efforts for several GPCR subtypes have failed to deliver selective drug candidates. Historically, drug discovery programmes for GPCR ligands have been dominated by efforts to devel...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2907734/ https://ncbi.nlm.nih.gov/pubmed/19116626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd2760 |
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