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Positive allosteric modulation of M(1) and M(4) muscarinic receptors as potential therapeutic treatments for schizophrenia

Current antipsychotic drugs provide symptomatic relief for positive symptoms of schizophrenia, but do not offer symptom management for negative and cognitive symptoms. In addition, many patients discontinue treatment due to adverse side effects. Therefore, there is a critical need to develop more ef...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuropharmacology
Prif Awduron: Yohn, Samantha E., Conn, P. Jeffrey
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844786/
https://ncbi.nlm.nih.gov/pubmed/28893562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2017.09.012
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