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Positive allosteric modulation of M(1) and M(4) muscarinic receptors as potential therapeutic treatments for schizophrenia

Current antipsychotic drugs provide symptomatic relief for positive symptoms of schizophrenia, but do not offer symptom management for negative and cognitive symptoms. In addition, many patients discontinue treatment due to adverse side effects. Therefore, there is a critical need to develop more ef...

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Detalhes bibliográficos
Publicado no:Neuropharmacology
Main Authors: Yohn, Samantha E., Conn, P. Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844786/
https://ncbi.nlm.nih.gov/pubmed/28893562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2017.09.012
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