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Muscarinic receptor M(4) positive allosteric modulators attenuate central effects of cocaine

BACKGROUND: Cocaine addiction is a chronic brain disease affecting neurotransmission. Muscarinic cholinergic receptors modulate dopaminergic signaling in the reward system, and muscarinic receptor stimulation can block direct reinforcing effects of cocaine. Here, we tested the hypothesis that specif...

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書誌詳細
出版年:Drug Alcohol Depend
主要な著者: Dall, Camilla, Weikop, Pia, Dencker, Ditte, Molander, Anna C., Wörtwein, Gitta, Conn, P. Jeffrey, Fink-Jensen, Anders, Thomsen, Morgane
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423356/
https://ncbi.nlm.nih.gov/pubmed/28544993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2017.03.014
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