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Muscarinic receptor M(4) positive allosteric modulators attenuate central effects of cocaine

BACKGROUND: Cocaine addiction is a chronic brain disease affecting neurotransmission. Muscarinic cholinergic receptors modulate dopaminergic signaling in the reward system, and muscarinic receptor stimulation can block direct reinforcing effects of cocaine. Here, we tested the hypothesis that specif...

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Bibliografische gegevens
Gepubliceerd in:Drug Alcohol Depend
Hoofdauteurs: Dall, Camilla, Weikop, Pia, Dencker, Ditte, Molander, Anna C., Wörtwein, Gitta, Conn, P. Jeffrey, Fink-Jensen, Anders, Thomsen, Morgane
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423356/
https://ncbi.nlm.nih.gov/pubmed/28544993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2017.03.014
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