Involvement of a Subpopulation of Neuronal M(4) Muscarinic Acetylcholine Receptors in the Antipsychotic-like Effects of the M(1)/M(4) Preferring Muscarinic Receptor Agonist Xanomeline

Disturbances in central dopaminergic neurotransmission are believed to be centrally involved in the pathogenesis of schizophrenia. Central dopaminergic and cholinergic systems interact and the cholinergic muscarinic agonist xanomeline has shown antipsychotic effects in clinical studies. Preclinical...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Dencker, Ditte, Wörtwein, Gitta, Weikop, Pia, Jeon, Jongrye, Thomsen, Morgane, Sager, Thomas N., Mørk, Arne, Woldbye, David P. D., Wess, Jürgen, Fink-Jensen, Anders
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6632952/
https://ncbi.nlm.nih.gov/pubmed/21508215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0370-11.2011
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