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An allosteric enhancer of M(4) muscarinic acetylcholine receptor function inhibits behavioral and neurochemical effects of cocaine
RATIONALE: The mesostriatal dopamine system plays a key role in mediating the reinforcing effects of psychostimulant drugs like cocaine. The muscarinic M(4) acetylcholine receptor subtype is centrally involved in regulation of dopamine release in striatal areas. Consequently, striatal M(4) receptors...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3914671/ https://ncbi.nlm.nih.gov/pubmed/22648127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-012-2751-8 |
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