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Diphenylpyrazoles as Replication Protein A Inhibitors
[Image: see text] Replication Protein A is the primary eukaryotic ssDNA binding protein that has a central role in initiating the cellular response to DNA damage. RPA recruits multiple proteins to sites of DNA damage via the N-terminal domain of the 70 kDa subunit (RPA70N). Here we describe the opti...
שמור ב:
| הוצא לאור ב: | ACS Med Chem Lett |
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| Main Authors: | , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Chemical
Society
2014
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| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4329576/ https://ncbi.nlm.nih.gov/pubmed/25699140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml5003629 |
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