Regulation of β-catenin by t-DARPP in upper gastrointestinal cancer cells

Por Vangamudi, Bhavatarini, Zhu, Shoumin, Soutto, Mohammed, Belkhiri, Abbes, El-Rifai, Wael
Publicado em 2011

t-DARPP regulates phosphatidylinositol-3-kinase-dependent cell growth in breast cancer

Por Vangamudi, Bhavatarini, Peng, Dun-Fa, Cai, Qiuyin, El-Rifai, Wael, Zheng, Wei, Belkhiri, Abbes
Publicado em 2010

Surface reengineering of RPA70N enables co-crystallization with an inhibitor of the RPA interaction motif of ATRIP

Por Feldkamp, Michael D., Frank, Andreas O., Kennedy, J. Phillip, Patrone, James D., Vangamudi, Bhavatarini, Waterson, Alex G., Fesik, Stephen W., Chazin, Walter J.
Publicado em 2013

Discovery of Protein–Protein Interaction Inhibitors of Replication Protein A

Por Patrone, James D., Kennedy, J. Phillip, Frank, Andreas O., Feldkamp, Michael D., Vangamudi, Bhavatarini, Pelz, Nicholas F., Rossanese, Olivia W., Waterson, Alex G., Chazin, Walter J., Fesik, Stephen W.
Publicado em 2013

Discovery of a Potent Stapled Helix Peptide That Binds to the 70N Domain of Replication Protein A

Por Frank, Andreas O., Vangamudi, Bhavatarini, Feldkamp, Michael D., Souza-Fagundes, Elaine M., Luzwick, Jessica W., Cortez, David, Olejniczak, Edward T., Waterson, Alex G., Rossanese, Olivia W., Chazin, Walter J., Fesik, Stephen W.
Publicado em 2014

Discovery of a Potent Inhibitor of Replication Protein A Protein-Protein Interactions Using a Fragment Linking Approach

Por Frank, Andreas O., Feldkamp, Michael D., Kennedy, J. Phillip, Waterson, Alex G., Pelz, Nicholas F., Patrone, James D., Vangamudi, Bhavatarini, Camper, DeMarco V., Rossanese, Olivia W., Chazin, Walter J., Fesik, Stephen W.
Publicado em 2013

Diphenylpyrazoles as Replication Protein A Inhibitors

Por Waterson, Alex G., Kennedy, J. Phillip, Patrone, James D., Pelz, Nicholas F., Feldkamp, Michael D., Frank, Andreas O., Vangamudi, Bhavatarini, Souza-Fagundes, Elaine M., Rossanese, Olivia W., Chazin, Walter J., Fesik, Stephen W.
Publicado no ACS Med Chem Lett (2014)

Identification and Optimization of Anthranilic Acid-Based Inhibitors of Replication Protein A

Por Patrone, James D., Pelz, Nicholas F., Bates, Brittney S., Souza-Fagundes, Elaine M., Vangamudi, Bhavatarini, Camper, Demarco V., Kuznetsov, Alexey G., Browning, Carrie F., Feldkamp, Michael D., Frank, Andreas O., Gilston, Benjamin A., Olejniczak, Edward T., Rossanese, Olivia W., Waterson, Alex G., Chazin, Walter J., Fesik, Stephen W.
Publicado no ChemMedChem (2016)

Development of novel cellular histone-binding and chromatin-displacement assays for bromodomain drug discovery

Por Zhan, Yanai, Kost-Alimova, Maria, Shi, Xi, Leo, Elisabetta, Bardenhagen, Jennifer P., Shepard, Hannah E., Appikonda, Srikanth, Vangamudi, Bhavatarini, Zhao, Shuping, Tieu, Trang N., Jiang, Shiming, Heffernan, Timothy P., Marszalek, Joseph R., Toniatti, Carlo, Draetta, Giulio, Tyler, Jessica, Barton, Michelle, Jones, Philip, Palmer, Wylie S., Geck Do, Mary K., Andersen, Jannik N.
Publicado no Epigenetics Chromatin (2015)

The SMARCA2/4 ATPase domain surpasses the bromodomain as a drug target in SWI/SNF mutant cancers: Insights from cDNA rescue and PFI-3 inhibitor studies

Por Vangamudi, Bhavatarini, Paul, Thomas A., Shah, Parantu K., Kost-Alimova, Maria, Nottebaum, Lisa, Shi, Xi, Zhan, Yanai, Leo, Elisabetta, Mahadeshwar, Harshad S., Protopopov, Alexei, Futreal, Andrew, Tieu, Trang N., Peoples, Mike, Heffernan, Timothy P., Marszalek, Joseph R., Toniatti, Carlo, Petrocchi, Alessia, Verhelle, Dominique, Owen, Dafydd R., Draetta, Giulio, Jones, Philip, Palmer, Wylie S., Sharma, Shikhar, Andersen, Jannik N.
Publicado no Cancer Res (2015)

Reduction of liver fibrosis by rationally designed macromolecular telmisartan prodrugs

Por Golder, Matthew R., Liu, Jenny, Andersen, Jannik N., Shipitsin, Michail V., Vohidov, Farrukh, Nguyen, Hung V.-T., Ehrlich, Deborah C., Huh, Sung Jin, Vangamudi, Bhavatarini, Economides, Kyriakos D., Neenan, Allison M., Ackley, James C., Baddour, Joelle, Paramasivan, Sattanathan, Brady, Samantha W., Held, Eric J., Reiter, Lawrence A., Saucier-Sawyer, Jennifer K., Kopesky, Paul W., Chickering, Donald E., Blume-Jensen, Peter, Johnson, Jeremiah A.
Publicado no Nat Biomed Eng (2018)