t-DARPP regulates phosphatidylinositol-3-kinase-dependent cell growth in breast cancer

BACKGROUND: Recent reports have shown that t-DARPP (truncated isoform of DARPP-32) can mediate trastuzumab resistance in breast cancer cell models. In this study, we evaluated expression of t-DARPP in human primary breast tumors, and investigated the role of t-DARPP in regulating growth and prolifer...

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Bibliographische Detailangaben
Hauptverfasser: Vangamudi, Bhavatarini, Peng, Dun-Fa, Cai, Qiuyin, El-Rifai, Wael, Zheng, Wei, Belkhiri, Abbes
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945963/
https://ncbi.nlm.nih.gov/pubmed/20836878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-240
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