Regulation of β-catenin by t-DARPP in upper gastrointestinal cancer cells

BACKGROUND: Truncated dopamine and cyclic-AMP-regulated phosphoprotein (t-DARPP) is frequently overexpressed in gastrointestinal malignancies. In this study, we examined the role of t-DARPP in regulating β-catenin. RESULTS: The pTopFlash construct that contains multiple TCF/LEF-binding sites was use...

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Main Authors: Vangamudi, Bhavatarini, Zhu, Shoumin, Soutto, Mohammed, Belkhiri, Abbes, El-Rifai, Wael
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075216/
https://ncbi.nlm.nih.gov/pubmed/21447180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-10-32
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