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Resistance to TRAIL is mediated by DARPP-32 in gastric cancer
PURPOSE: Dopamine and cAMP-regulated phosphoprotein, Mr 32000 (DARPP-32), is overexpressed during the gastric carcinogenesis cascade. Here, we investigated the role of DARPP-32 in promoting resistance to treatment with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). EXPERIMENTAL DES...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3399047/ https://ncbi.nlm.nih.gov/pubmed/22589394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-3182 |
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