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Activation of IGF1R by DARPP-32 promotes STAT3 signaling in gastric cancer cells
Dopamine and cAMP-regulated phosphoprotein, Mr 32000 (DARPP-32), is frequently overexpressed in earlt stages of gastric cancers. We utilized in vitro assays, 3D gastric gland organoid cultures, mouse models, and human tissue samples to investigate the biological and molecular impact of DARPP-32 on a...
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| Publicado no: | Oncogene |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6639157/ https://ncbi.nlm.nih.gov/pubmed/31235784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-019-0843-1 |
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