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Helicobacter pylori-induced cell death is counteracted by NF-κB-mediated transcription of DARPP-32

OBJECTIVE: DARPP-32 is a frequently amplified and overexpressed gene that promotes several oncogenic functions in gastric cancer. Herein, we investigated the relationship between Helicobacter pylori infection, proinflammatory NF-κB activation and regulation of DARPP-32. DESIGN: The study used in viv...

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Bibliographic Details
Published in:Gut
Main Authors: Zhu, Shoumin, Soutto, Mohammed, Chen, Zheng, Peng, DunFa, Romero-Gallo, Judith, Krishna, Uma S, Belkhiri, Abbes, Washington, M Kay, Peek, Richard, El-Rifai, Wael
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334457/
https://ncbi.nlm.nih.gov/pubmed/27590997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2016-312141
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