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Resistance to TRAIL is mediated by DARPP-32 in gastric cancer

PURPOSE: Dopamine and cAMP-regulated phosphoprotein, Mr 32000 (DARPP-32), is overexpressed during the gastric carcinogenesis cascade. Here, we investigated the role of DARPP-32 in promoting resistance to treatment with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). EXPERIMENTAL DES...

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Detaylı Bibliyografya
Asıl Yazarlar: Belkhiri, Abbes, Zhu, Shoumin, Chen, Zheng, Soutto, Mohammed, El-Rifai, Wael
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399047/
https://ncbi.nlm.nih.gov/pubmed/22589394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-3182
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