Epidermal Growth Factor-Induced Tumor Cell Invasion and Metastasis Initiated by Dephosphorylation and Downregulation of Focal Adhesion Kinase

Por Lu, Zhimin, Jiang, Guoqiang, Blume-Jensen, Peter, Hunter, Tony
Publicado em 2001

Discovery of PDK1 Kinase Inhibitors with a Novel Mechanism of Action by Ultrahigh Throughput Screening

Por Bobkova, Ekaterina V., Weber, Michael J., Xu, Zangwei, Zhang, Yan-Ling, Jung, Joon, Blume-Jensen, Peter, Northrup, Alan, Kunapuli, Priya, Andersen, Jannik N., Kariv, Ilona
Publicado em 2010

Automated quantitative multiplex immunofluorescence in situ imaging identifies phospho-S6 and phospho-PRAS40 as predictive protein biomarkers for prostate cancer lethality

Por Shipitsin, Michail, Small, Clayton, Giladi, Eldar, Siddiqui, Summar, Choudhury, Sibgat, Hussain, Sadiq, Huang, Yi E, Chang, Hua, Rimm, David L, Berman, David M, Nifong, Thomas P, Blume-Jensen, Peter
Publicado em 2014

Identification of Direct Target Engagement Biomarkers for Kinase-Targeted Therapeutics

Por Paweletz, Cloud P., Andersen, Jannik N., Pollock, Roy, Nagashima, Kumiko, Hayashi, Mansuo L., Yu, Shangshuan U., Guo, Hongbo, Bobkova, Ekaterina V., Xu, Zangwei, Northrup, Alan, Blume-Jensen, Peter, Hendrickson, Ronald C., Chi, An
Publicado em 2011

Reduction of liver fibrosis by rationally designed macromolecular telmisartan prodrugs

Por Golder, Matthew R., Liu, Jenny, Andersen, Jannik N., Shipitsin, Michail V., Vohidov, Farrukh, Nguyen, Hung V.-T., Ehrlich, Deborah C., Huh, Sung Jin, Vangamudi, Bhavatarini, Economides, Kyriakos D., Neenan, Allison M., Ackley, James C., Baddour, Joelle, Paramasivan, Sattanathan, Brady, Samantha W., Held, Eric J., Reiter, Lawrence A., Saucier-Sawyer, Jennifer K., Kopesky, Paul W., Chickering, Donald E., Blume-Jensen, Peter, Johnson, Jeremiah A.
Publicado no Nat Biomed Eng (2018)

Genetic and Pharmacological Inhibition of PDK1 in Cancer Cells: CHARACTERIZATION OF A SELECTIVE ALLOSTERIC KINASE INHIBITOR

Por Nagashima, Kumiko, Shumway, Stuart D., Sathyanarayanan, Sriram, Chen, Albert H., Dolinski, Brian, Xu, Youyuan, Keilhack, Heike, Nguyen, Thi, Wiznerowicz, Maciej, Li, Lixia, Lutterbach, Bart A., Chi, An, Paweletz, Cloud, Allison, Timothy, Yan, Youwei, Munshi, Sanjeev K., Klippel, Anke, Kraus, Manfred, Bobkova, Ekaterina V., Deshmukh, Sujal, Xu, Zangwei, Mueller, Uwe, Szewczak, Alexander A., Pan, Bo-Sheng, Richon, Victoria, Pollock, Roy, Blume-Jensen, Peter, Northrup, Alan, Andersen, Jannik N.
Publicado em 2011